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Starting with basic principles, this reference and handbook discusses examples of the most advanced models of bacterial infection with regard to their value as paradigms to understand the molecular cross talks between microbes and their host and tissue targets. It adopts a very forward-looking, advanced approach, placing special emphasis on the main global challenges facing scientists today, such as pathogenicity vs. commensalisms, infections in immunocompromised hosts and species speciﬁcity issues.
"Bacterial Virulence: Basic Principles, Models and Global Approaches" is the second title in Wiley-Blackwell''s ''Infection Biology Handbook Series''. The first is "Aids and Tuberculosis: A Deadly Liaison," edited by two of the most accomplished experts in this area, Prof. Dr. Dr. h.c. Stefan Kaufmann at the Max-Planck Institute for infectious diseases in Berlin, Germany, and Prof. Dr. Bruce Walker, director of the Ragon Institute of MGH, MIT and Harvard in Boston, USA.