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Cilia: Model Organisms & Intraflagellar Transport : Cilia: Model Organisms and Intraflagellar Transport (Hardcover)

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Product Overview

Cilia are highly conserved organelles that serve motile functions,?sensory functions, or both. These organelles power cell movement, generate fluid flow in various organs, act as sensors of the extracellular environment and have been modified for various specialized tasks such as light reception and smell. Defects in these ubiquitous organelles lead to a broad array of human genetic disorders that range from polycystic kidney disease, retinal degeneration, epilepsy and infertility to developmental defects such as situs inversus and polydactyly. This volume is the third in a three-part series on cilia that focuses on the use of model organisms to gain insight into ciliary function and on the process of intraflagellar transport (IFT) that is essential for the assembly and maintenance of ciliary structures.

* Includes both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time * Covers forward and reverse genetic analysis of IFT and bochemical methods to define the role of IFT components * Methods?presented cover molecular,?genetic, and biochemical approaches to ciliary function in model organisms

Specifications

Publisher Academic Pr
Mfg Part# 9780123813770
SKU 212752581
Format Hardcover
ISBN10 0123813778
Release Date 12/1/2009
Product Attributes
eBooks Kobo
Book Format Hardcover
Number of Pages 0390
Publisher Academic Press
Series Part 93
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