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|DHEA is a natural steroid hormone that is synthesized from cholesterol through pregnenelone by the adrenal glands. DHEA acts as an antagonist for glucocorticosteroid hormones and is the parent precursor for other important steroid hormones, such as estradiol and other estrogens, and testosterone. While not a precursor to progesterone, DHEA can indirectly influence progesterone synthesis through a feedback mechanism whereby pregnenelone is converted to progesterone based on DHEA levels. Apart fro|