Kilt-wearing master chemist Elmo McElroy (Samuel L. Jackson) has developed a new drug that is more potent then cocaine or Ecstasy. Best of all, none of the ingredients are illegal, meaning that this substance could easily be sold worldwide. Unfortunately for McElroy, he is caught in the snare of psychotic drug kingpin The Lizard (Meat Loaf). McElroy's attempts to escape his boss and start a new life land him in Liverpool, England, where he encounters Felix DeSouza (Robert Carlyle), the America-hating henchman of a local drug lord. De Souza and McElroy find themselves on a wild, dangerous ride as they try to make a deal that will net them some major cash and give them a chance to start over. In the meantime, Dakota (Emily Mortimer)--a beautiful assassin who happens to be DeSouza's ex-girlfriend--is sent by The Lizard to kill McElroy, but ends up becoming his guardian angel. The quirky cast of characters also includes Rhys Ifans as Iki, a disturbed drug dealer and rave host; Sean Pertwee as Detective Virgil Kane; Ricky Tomlinson as the hemorrhoid-plagued Leopold Durant; and, a group of skinheads who want in on the deal. The film is directed by Ronny Yu (BRIDE OF CHUCKY).