Hyaluronan in Cancer Biology (Hardcover)

Customer Reviews   Write a Review

Be the first to review this item and earn 25 Rakuten Super Points™

Product Overview

Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal.

The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer.

* Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer

* Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination

* Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance

Specifications

Publisher Academic Pr
Mfg Part# 9780123741783
SKU 210693287
Format Hardcover
ISBN10 0123741785
Release Date 4/1/2009
Product Attributes
eBooks Kobo
Book Format Hardcover
Number of Pages 0426
Publisher Academic Press
loading
Sold Out
Sorry, you missed the deal!
This product is currently not available.
ADVERTISEMENT
Buy From Other Sellers (0)
kobo
  • Take your library with you wherever you go
  • Use the device you want to use… smartphone, desktop and many of today’s most popular eReaders

WHY KOBO?

We love the Kobo eReading service… and we know you will too. We’ve partnered with them to bring you the most flexible, enjoyable eReading experience in the U.S.

SHOPPING ON KOBO

You’ll be asked to sign in or create a new account with Kobo. Once you do, you’ll immediately get access to millions of titles and be ready to start eReading. Anytime. Anyplace.

continue to kobo
ADVERTISEMENT
ADVERTISEMENT