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Summarizing the contribution that insertional mutagenesis has made to our understanding of cancer, this volume presents various insertional mutagens as well as their impact in gene therapy trials. The book also recommends strategies for future clinical trials.
From the Publisher:
The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.