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Intravascular thrombus formation remains one of the most significant problems in cardiovascular medicine and a major risk in many interventional procedures. Today, clinicians have a wide choice of antithrombotic and anticoagulant agents available, including aspirin, thienopyridines, platelet glycoprotein IIb/IIIa inhibitors, low molecular weight heparins, thrombin inhibitors, and fibrinolytic agents. Though effective, all of these agents possess limitations, the most common being an increased risk of bleeding. Implementing the most appropriate, and safe, anticoagulation therapy across the spectrum of cardiovascular disease, in the presence of a wide range of other risk factors, remains a challenge.
Incorporating the most up to date evidence-based review of each class of agents, this book acquaints readers with the data behind the commonly used anti-thrombotic agents and will assist them in formulating a sound, therapeutic strategy appropriate for each patient.