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Protein Misfolding Diseases : Current and Emerging Principles and Therapies (Hardcover)

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Product Overview

Protein misfolding/aggregation diseases are a medical puzzle that has baffled researchers for many years. These diseases are characterized by the presence of protein deposits, or amyloid fibrils, which gather in the intracellular and/or extracellular spaces in a variety of tissues. Unchecked, the process of amyloidogenesis leads to proteotoxicity, cell loss, and eventually organ dysfunction, and causes such well-known and devastating diseases as Alzheimer's, Parkinson's, and Mad Cow.

Employing a diversity of research approaches, including chemical and biophysical, cellular, and animal models, the authors investigate various amyloid diseases and outline progress made in understanding them in this important book. Included are novel strategies to combat a wide variety of degenerative diseases.

Protein Misfolding Diseases uses the latest medical data from expert scientists and protein misfolding clinicians to launch a multi-targeted assault on the process of amyloid fibril formation. Fresh insight into the etiology of these maladies helps researchers gain a thorough understanding of the bases of these diseases and offers guidance in designing therapeutic strategies to build on promising new findings---and bring hope one step closer to reality.

Specifications

Publisher John Wiley & Sons Inc
Mfg Part# 9780471799283
SKU 212447596
Format Hardcover
ISBN10 0471799289
Release Date 6/1/2010
Product Attributes
eBooks Kobo
Book Format Hardcover
Number of Pages 1045
Publisher John Wiley & Sons
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