Receptor Localization: Laboratory Methods and Procedures (Paperback)

Customer Reviews   Write a Review

Be the first to review this item and earn 25 Rakuten Super Points™

Product Overview

The detection of neurotransmitter receptor locations and distribution densities within the central nervous system and peripheral tissues is receiving intense attention within the neuroscience research community. Neurotransmitter receptors, which receive the chemical signals sent from one neuron to another, are critical links in a highly complex information-processing chain. Pinpointing receptor sites and systems is crucial for understanding neurological function as well as dysfunction. It is also essential for understanding how receptors process information when impacted by such substances as heroin or nicotine, or when affected by neurodegenerative disease.

"Receptor Localization: Laboratory Methods and Procedures" is the first user-friendly guide to the latest techniques and approaches being employed to examine the localization of neurotransmitter receptors in the central nervous system and peripheral tissues. It covers detection methods that are applicable to a wide variety of receptor systems, ranging from genes and ligands to in vivo receptors in individuals; and to numerous receptor subtypes, such as nicotine, muscarine, tachykinins, dopamine, adenosine, and GABA. The standard laboratory "recipes" or "tricks" employed in these detection methods are fully discussed, as are the advantages and limitations of each procedure. With contributions from leading experts and extensively illustrated, this book: Discusses receptor ligand binding methods using irreversible and reversible compounds Presents antireceptor antisera technology using synthetic peptides and fusion proteins at both the cellular and subcellular resolution levels Examines molecular assessments of receptors Describesin situ hybridization, reverse transcriptase-PCR, and fluorescent in situ transcription Covers new visualization paradigms Includes physiological analysis of receptor function, cellular detection in the brain slice, and cultured neurons Discusses the use of PET and SPECT to assess in vivo receptor distributions in animals and humans.

"Receptor Localization: Laboratory Methods and Procedures" is an invaluable guide for researchers in the related fields of neuroscience, neurology, biochemistry, and pharmacology. Its lucid descriptions of new detection methods, inclusion of experimental examples, and emphasis on how these experimental approaches are applicable to particular research areas will appeal to both the experienced researcher and novice investigator.

Specifications

Publisher Wiley-Liss
Mfg Part# 9780471195245
SKU 203132941
Format Paperback
ISBN10 0471195243
Release Date 8/13/2012
loading
$215.31 + $5.98 shipping
Rakuten Super Points Earn 216 ($2.16) Rakuten Super Points™
What are Rakuten Super Points™?
Get rewarded when you shop! Earn 1 point per dollar spent. That's like getting cash back on every purchase. Easy to see matured points in checkout. Use points just like cash.
Learn More
Get this item for
(price with shipping)
(redeem points)
Format: Paperback
Condition: Used-Good
In Stock. Usually Ships in 1 to 2 business days
Please select an option to buy
Add to Cart

What is a Marketplace and Shop Owner?
  • Our marketplace is a platform where approved third-party retailers (Shop Owners) can sell their products
  • Items are sold and shipped by Shop Owners
  • Your credit card and personal information remain secure; Rakuten.com meets all PCI Security Standards.
  • Purchases can only be returned to the Shop Owner
  • All purchases receive Rakuten Super Points™
ADVERTISEMENT
Promotions & Offers (1)
  •  custom promo
    5% Back* Sitewide with Promo Code Rewardme *See page for details
ADVERTISEMENT
ADVERTISEMENT